Synonyms
(((Carboxymethyl)imino)bis(ethylenenitrilo))tetraacetic acid; (Diethylenetrinitrilo)pentaacetic acid; 2,2'-(Carboxymethylimino)bis(ethyliminodiessigsaeure); 3,6,9-Triazaundecanedioic acid, 3,6,9-tris(carboxymethyl)-; Acetic acid, ((carboxymethylimino)bis(ethylenenitrilo))tetra-; Acetic acid, 2,2',2'',2'''-(((carboxymethyl)imino)bis(2,1-ethanediylnitrilo))tetrakis-; Acide pentetique [INN-French]; Acido pentetico [INN-Spanish]; Acidum penteticum [INN-Latin]; CHEL 330 acid; Chel DTPA; Complexon V; DTPA; Dabeersen 503; Detapac; Detarex; Diethylenetriamine-N,N,N',N'',N''-pentaacetic acid; Diethylenetriaminepentaacetic acid; Dissolvine D; Glycine, N,N-bis(2-(bis(carboxymethyl)amino)ethyl)-; Hamp-Ex Acid; Monaquest CAI; N,N-Bis(2-(bis(carboxymethyl)amino)ethyl)glycine; Pentacarboxymethyldiethylenetriamine; Penthamil (VAN); Perma kleer; Titriplex V; N-Carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid); 1,1,4,7,7-Diethylenetriaminepentaacetic acid; [ChemIDplus]
Sources/Uses
Used as a chelating agent; [Merck Index] "An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium." [ChemIDplus] Used in cosmetic products, in industrial metal extraction, and therapeutically; [ExPub: TERIS]
Comments
The calcium salt causes fetal death and teratogenic effects in mice (thought to be associated with the chelation of essential divalent cations such as zinc); [REPROTOX] Causes convulsions and chronic pulmonary edema in intraperitoneal lethal-dose studies of rats (LD50 = 587 mg/kg); [RTECS] An eye irritant; [Acros Organics MSDS] See "Edetic acid."