Stoddard solvent

Agent Name
Stoddard solvent
CAS Number
Major Category
Dry cleaning safety solvent; Mineral spirits; Petroleum solvent; Spotting naphtha; [NIOSH] Texsolve S; Varsol; [ATSDR Case Studies # 33] UN1993
Petroleum, Refined
Colorless liquid with a kerosene-like odor. Stoddard solvent is a mixture of straight and branched chain paraffins (48%), naphthenes (38%) and aromatic hydrocarbons (14%).The odor threshold is 1 to 30 ppm. [ACGIH]
Stoddard solvent has been used as a paint thinner and general purpose industrial solvent. It has been used in dry cleaning. [ACGIH] In semiconductor manufacturing, Stoddard solvent is used to "develop" the pattern in the photoresists; [CHS, p. 44]
TSCA Definition 2008: A petroleum distillate, free from objectionable odors, that boils in the range of 149.deg C to 204.5.deg C; [ChemIDplus] Stoddard solvent and other petroleum distillates (VM & P naphtha and kerosene) can cause anesthesia, slowing of reflexes, and dermatitis. Stoddard solvent may contain n-hexane with the potential to cause peripheral neuropathy. [LaDou, p. 543] Aliphatic and aromatic hydrocarbons cause trivial hepatic injury in animal experiments. [Haddad, 226t] See "Solvent naphtha (petroleum), medium aliphatic."
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
100 ppm
500 ppm
3390 ppm
Excerpts from Documentation for IDLHs
Human data: It has been reported that the atmospheric concentration immediately hazardous to life is probably between 5,000 and 10,000 ppm when high temperature or other factors make these concentrations attainable and exposure to levels approaching 5,000 ppm should be avoided [Rector et al. 1966]. [Note: A concentration of 5,000 ppm is equivalent to about 29,500 mg/m3 assuming an approximate molecular weight of 144 for Stoddard solvent.]
Vapor Pressure
1.5 mm Hg
Odor Threshold Low
1 ppm
Lethal Concentration
LC (rat) = >5,500 mg/m3/4H
Explanatory Notes
IDLH = 20,000 mg/m3 which is 3390 ppm assuming a MW of 144; Odor threshold (<1 ppm) from CHEMINFO; Flash point = 110 deg F; VP from HSDB;
high ambient temp required

Adverse Effects

Acute solvent syndrome
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: