1-Dodecanethiol
Agent Name
1-Dodecanethiol
Alternative Name
Dodecyl mercaptan
CAS Number
112-55-0
Formula
C12-H26-S
Major Category
Other Classes
Synonyms
1-Dodecyl mercaptan; n-Dodecyl mercaptan; Lauryl mercaptan; n-Lauryl mercaptan; 1-Mercaptododecane; [NIOSH]
Category
Thiols
Description
Colorless, water-white, or pale-yellow, oily liquid with a mild, skunk-like odor; Note: A solid below 15 degrees F; [NIOSH]
Sources/Uses
Used in the production of drugs, insecticides, detergents, and synthetic rubber and as a flotation agent for metal refining; [ACGIH]
Comments
This chemical is listed in the Chemotechnique Diagnostics "Shoe Series" for patch testing. [Marks, p. 376] Not highly toxic after acute exposure; Rats and mice had no adverse effects after exposure to 8-9 ppm for 1 to 6 hours. Some mice died after exposure to 8 ppm (6 hours/day, 5 days/week for 4 weeks); No adverse effects in rats exposed to 329 ppm (twenty 6-hour exposures); A dermal sensitizer; [ACGIH] Danger of skin sensitization; [MAK] See "THIOLS."
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
0.1 ppm
Vapor Pressure
0.00853 mm Hg
Odor Threshold Low
0.00025 ppm
Explanatory Notes
NIOSH REL = 15 min. ceiling of 0.5 ppm; Flash point = 128 deg C; Odor threshold from ACGIH; VP from HSDB;
NFPA
must be preheated
Adverse Effects
Skin Sensitizer
Yes
Other Poison
Chemical Asphyxiant
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: