1-Dodecanol

Synonyms

Lauryl alcohol; 1-Dodecyl alcohol; 1-Hydroxydodecane; Adol 10; Adol 11; Adol 12; Alcohol C-12; Alfol 12; C12 alcohol; CO-1214; CO-1214N; CO-1214S; Cachalot L-50; Cachalot L-90; Conol 20P; Conol 20PP; Duodecyl alcohol; Dytol J-68; Dytol J-68 (VAN); EPAL 12; Fatty alcohol(C12); Hainol 12SS; Karukoru 20; Lauric alcohol; Laurinic alcohol; Lauroyl alcohol; Lauryl 24; Lauryl alcohol; Lorol 11; Lorol 5; Lorol 7; Lorol C 12; Lorol C 12/98; MA-1214; Pisol; S 1298; Sipol L12; Siponol 25; Siponol L2; Siponol L5; Undecyl carbinol; n-Dodecan-1-ol; n-Dodecyl alcohol; n-Lauryl alcohol, primary; Dodecanol; Dodecyl alcohol; [ChemIDplus]

Category

Alcohols and Polyols, Other

Description

Colorless solid below 20 deg C; Colorless liquid at room temperature; Unpleasant odor at high concentrations; Delicate floral odor when diluted; [HSDB] White solid with an alcohol-like odor; mp = 26 deg C; [MSDSonline]

Sources/Uses

Used to manufacture sulfuric acid esters (wetting agents) and in synthetic detergents, lube additives, pharmaceuticals, rubber, textiles, and perfumes; Also used as a flavoring agent and as a foam stabilizer for alcohol sulfate surfactants; [HSDB] Used to make surfactants for detergents, cleaning products, shampoos, cosmetics, lubricants, wetting agents, emulsifiers, dispersing agents, and antioxidants; Also used to make biocides and disinfectants; 1-Dodecanol is used in foam control, aluminum rolling, metalworking, and in the rubber, textiles, cosmetics, and perfume industries; Also used as a froth flotation agent and a flavoring ingredient in non-alcoholic beverages, ice cream, candy, baked goods, chewing gum, and syrups; [CHEMINFO] Used as Lepidoptera pheromone in apple and pear orchards; [EPA]

Comments

Higher alcohols are not highly toxic in the industrial setting; Can cause liver injury, somnolence, and respiratory depression in experimental animals; A skin and eye irritant; [HSDB] Inhalation of high concentrations may cause CNS depression; [CHEMINFO] Safe when used as a flavoring agent in food; [JECFA] Practically nontoxic and generally recognized as safe (GRAS) in food; [Reference #1] Causes general depressed activity after administration onto skin of rabbit; [RTEC] An irritant; [MSDSonline]

Biomedical References

0.000848 mm Hg

LC50 (rat) > 1,050 mg/m3/6h

Explanatory Notes

Flash point = 127 deg C; [HSDB] VP from ChemIDplus;

must be preheated

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Aluminum Producing
• Metal Machining
• Textiles (Fiber & Fabric Manufacturing)