N,N-Dimethylaminoethyl methacrylate

Synonyms

2-(Dimethylamino)ethyl 2-methyl-2-propenoate; 2-(Dimethylamino)ethyl methacrylate; Dimethylaminoethyl methacrylate; 2-(Dimethylamino)ethyl methacrylate; 2-(N,N-Dimethylamino)ethyl methacrylate; 2-Dimethylaminoethyl methacrylate; 2-Dimethylaminoethylester kyseliny methakrylove [Czech]; 2-Propenoic acid, 2-methyl-, 2-(dimethylamino)ethyl ester; Ageflex FM-1; Ethanol, 2-(dimethylamino)-, methacrylate; Methacrylic acid, 2-(dimethylamino)ethyl ester; N,N-Dimethylethanolamine methacrylate; beta-Dimethylaminoethyl methacrylate; [ChemIDplus] MADAME; DAM; [eChemPortal: SIDSUNEP] UN2522

Category

(Meth)acrylates

Description

Colorless to light yellow liquid; [ICSC] Clear light yellow liquid; [MSDSonline]

Sources/Uses

Used in binders for coatings, textile chemicals, dispersing agents for non-aqueous systems, antistatic agents, stabilizers for chlorinated polymers, ion exchange resins, emulsifying agents, cationic precipitating agents, dental materials, antithrombogenic prosthetics, and cosmetics; Used as comonomer (for polymers used in water treatment, architectural paints, viscosity index improvers, and adhesives), monomer for its homopolymer, and to make its acetate and nitrate salts; [HSDB]

Comments

May polymerize on exposure to heat, light, oxidants, reducing agents, or metals causing fire or explosion; A respiratory tract irritant; Corrosive to skin and eyes; [ICSC] A skin, eye, and mucous membrane irritant; In gavage studies of rabbits, electrical brain activity was suppressed followed by clonic-tonic spasms; Highly irritating to skin and eyes, based on animal studies; [HSDB] Heat or contamination can cause exothermic polymerization; Corrosive to eyes and mucous membranes; [CAMEO] Effects in repeated dose feeding studies with rats include late onset chronic convulsions and nerve fiber degeneration in the brain and spinal cord; Corrosive to skin and eyes, based on animal studies; [eChemPortal: SIDSUNEP] Corrosive to skin and eyes; [eChemPortal: ERMA] A skin and eye irritant; May cause skin sensitization; [eChemPortal: ESIS] Danger of skin sensitization; [MAK] A severe irritant that may cause burns; A possible lachrymator and skin sensitizer; [MSDSonline] 2-Dimethylaminoethyl methacrylate (UN2522) has warning of explosive polymerization; [ERG 2016] See "ACRYLIC RESINS (MONOMERS)."

Biomedical References

0.829 mm Hg

LC50 (rat) = 620 mg/m3/4h

Yes

Explanatory Notes

VP from ChemIDplus;

high ambient temp required

Yes

Yes

Other CNS neurotoxin

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Painting (Pigments, Binders, and Biocides)
• Sewer and Wastewater Treatment
• Textiles (Fiber & Fabric Manufacturing)
• Working with Glues and Adhesives