Phenoxarsine oxide
Agent Name
Phenoxarsine oxide
CAS Number
58-36-6
Formula
C24-H16-As2-O3
Major Category
Metals
Synonyms
10,10'-Bis(phenoxyarsinyl) oxide; 10,10'-Oxidiphenoxarsine; 10,10'-Oxybis-10H-phenoxarsine; 10,10'-Oxybisphenoxarsine; 10,10'-Oxybisphenoxy-arsine; 10,10'-Oxydiphenoxarsine; 10-10' Oxybisphenoxyarsine; 10H-Phenoxarsine, 10,10'-oxybis-; Bis(10-phenoxarsinyl)oxide; Bis(10-phenoxarsyl) oxide; Bis(10-phenoxyarsinyl) oxide; Bis(phenoxarsin-10-yl) ether; DID 47; Durotex; OBPA; Phenoxarsine, 10,10'-oxydi-; Phenoxyarsine, 10,10'-oxybis-; SA 546; Vinadine; Vinyzene; Vinyzene (pesticide); Vinyzene BP 5; Vinyzene BP 5-2; Vinyzene SB 1; 10H-Phenoxarsine, 10,10'-oxybis-; Diphenoxarsin-10-yl oxide; [ChemIDplus]
Category
Arsenic Compounds, Organic
Description
Colorless solid; [Merck Index] White crystalline solid; [MSDSonline]
Sources/Uses
Used to protect plastics and textiles from fungi and bacteria; [HSDB] Used as a bacteriocide/germicide and fungicide in shower curtains, floor and wall coverings, coated fabrics, marine upholstery, vinyl moldings, awnings, weather stripping, and swimming pool liners; Also used as a preservative in adhesives, coatings, carpets, and other products (paper, plastic, and textile); [EPA REDs]
Comments
Severely irritating to skin; Toxic by ingestion and inhalation; Oral LD50 (rat) = 40 mg/kg; [Sax] Retards growth and causes liver effects in high-dose feeding studies; No developmental, reproductive, or mutagenic effects; Arsenic accumulates in liver and kidneys of exposed animals with clearing 2 weeks after last exposure; "The potential for occupational exposure to OBPA is minimal provided that OBPA is used in a closed system and that appropriate Personal Protective Equipment (PPE) is worn." [EPA REDs] An irritant that can cause skin burns; May be lethal if ingested or inhaled; May cause liver and kidney damage; [MSDSonline] "Almost nothing is known regarding health effects of organic arsenic compounds in humans. Studies in animals show that some simple organic arsenic compounds are less toxic than inorganic forms. Ingestion of methyl and dimethyl compounds can cause diarrhea and damage to the kidneys." [ATSDR ToxProfiles]
Reference Link #1
Biomedical References
Exposure Assessment
PEL (OSHA)
0.5 mg/m3, as As
Lethal Concentration
LCLo (guinea pigs) = 141 mg/m3/2h
Adverse Effects
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes