Isophorone diamine

Agent Name
Isophorone diamine
CAS Number
Major Category
Nitrogen Compounds
Isophorone diamine formula graphical representation
3-Aminomethyl-3,5,5-trimethylcyclohexylamine; 5-Amino-1,3,3-trimethylcyclohexanemethylamine; Cyclohexanemethanamine, 5-amino-1,3,3-trimethyl-; Cyclohexanemethylamine, 5-amino-1,3,3-trimethyl-; 3-Aminomethyl-3,5,5-trimethylcyclohexylamine; Cyclohexanemethanamine, 5-amino-1,3,3-trimethyl-; Isophoronediamine; [ChemIDplus] 1,3,3-Trimethyl-1-aminomethyl-5-aminocyclohexane; 1-Amino-3,3,5-trimethyl-5-aminomethylcyclohexane; 1-Amino-3-(aminomethyl)-3,5,5-trimethylcyclohexane; 3,3,5-Trimethyl-5-aminomethylcyclohexylamine; 3-Aminomethyl-3,5,5-trimethylcyclohexylamine; 5-Amino-1,3,3-trimethylcyclohexanemethanamine; Araldite HY 5083; Chemammina CA 17; IPD; Isoforondiamina (Spanish DOT); Isophoronediamine (French DOT); Luxam IPD; Vestamin IPD; [CAMEO] 1-Amino-3-aminomethyl-3,5,5-trimethylcyclohexane; 3-Aminomethyl-3,5,5-trimethylcyclohexylamin (German); Degamin IPDA; Isophorondiamin (German); [Reference #2] UN2289
Amines, Cyclic
Colourless liquid; mp = 10 deg C; [ICSC] Clear light yellow liquid; [Aldrich MSDS]
Used to make its corresponding diisocyanate, polymers (mainly polyurethanes), and to cure epoxy resins; [HSDB] Used to make hardeners for epoxy resins and coatings (and directly as a hardener), in epoxy-based self-leveling and trowelable flooring systems, for paving, concrete protection, and repair, in coatings for corrosion protection of metal, adhesives, and anchoring compounds, and in paints; Also used to make dyes and non-crystalline specialty polyamides; [Reference #2]
If inhaled, it can provoke coughing and nausea. [CHRIS] An epoxy resin hardener and suspected cause of occupational asthma, isophorone diamine is one component of mixtures causing occupational asthma in two separate documented cases: (1) [Occupational asthma due to EPO 60. Lambourn EM, Hayes JP, McAllister WA, Taylor AJ. Br J Ind Med 1992 Apr;49(4):294-5]; and (2) [Occupational asthma caused by a hardener containing an aliphatic and a cycloaliphatic diamine. Aleva RM et al. Am Rev Respir Dis 1992 May;145(5):1217-8] Corrosive to skin, eyes, and respiratory tract; Inhalation can cause pulmonary edema; May cause skin sensitization. [ICSC] Danger of skin sensitization; [MAK] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion; [Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
0.015 mm Hg
Explanatory Notes
Flash point =112 deg C; Vapour pressure, Pa at 20°C: 2; [ICSC]

Adverse Effects

Skin Sensitizer
Toxic Pneumonitis
Skin burns

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: