Hexamethylene tetramine

Agent Name
Hexamethylene tetramine
CAS Number
Major Category
Nitrogen Compounds
Hexamethylene tetramine formula graphical representation
1,3,5,7-Tetraazaadamantane; 1,3,5,7-Tetraazatricyclo (,7))decane; 1,3,5,7-Tetraazatricyclo( 3,7))decane; 1,3,5,7-Tetraazatricyclo( 37))decane; Aceto HMT; Aminoform; Aminoformaldehyde; Ammoform; Ammonioformaldehyde; Antihydral; Cystamin; Cystogen; Duirexol; Ekagom H; Esametilentetramina [Italian]; Formamine; Formin; Formin (heterocycle); HMT; Herax UTS; Heterin; Hexa (vulcanization accelerator); Hexa-Flo-Pulver; Hexaform; Hexaloids; Hexamethylenamine; Hexamethyleneamine; Hexamethylenetetraamine; Hexamethylenetetramine; Hexamethylenetetraminum; Hexamethylentetramin [German]; Hexamethylentetramine; Hexamethylentetraminum; Hexamine; Hexamine (heterocycle); Hexaminum; Hexasan; Hexasan (VAN); Hexilmethylenamine; Metenamina [INN-Spanish]; Methenamin; Methenamine; Methenaminum [INN-Latin]; Metramine; Nocceler H; Preparation AF; Resotropin; S 4 (heterocycle); Sanceler H; Uramin; Uratrine; Uritone; Urodeine; Urotropin; Urotropine; Vulkacit H 30; Xametrin; [ChemIDplus] UN1328
Amines, Aliphatic
White, crystalline powder or colorless, lustrous crystals; [HSDB]
Used in adhesives, coatings, sealants, and leather preservatives; also used as an anticorrosion agent, antibiotic, dye fixative, chemical stabilizer, and curing agent for formaldehyde resins and rubber; [HSDB] Used as a drug (methenamine) taken by mouth to prevent recurrent urinary tract infections; [Medscape DrugInfo] Used as a hardener for epoxy resins of the bisphenol A type; Used in the tire, rubber, foundry, and phenol-formaldehyde resin industries; Sometimes used in topical drugs and cosmetics; [Kanerva, p. 1811] Used as a formaldehyde releaser for photographic film development. [Kanerva, p. 1054-5]
A skin and eye irritant; A skin sensitizer; May cause asthma; [ICSC] Danger of skin sensitization; [MAK] TLV Basis is dermal sensitization. No evidence of increased risk of occupational asthma at concentrations of 0.2-2.6 mg/m3.
Biomedical References

Exposure Assessment

1 mg/m3, inhalable fraction and vapor
Vapor Pressure
0.004 mm Hg
Explanatory Notes
Flash point = 482 deg F; VP from ACGIH;
Reference Link #2

Adverse Effects

Skin Sensitizer
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: