Hexamethylene tetramine

Synonyms

1,3,5,7-Tetraazaadamantane; 1,3,5,7-Tetraazatricyclo (3.3.1.1(3,7))decane; 1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 3,7))decane; 1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 37))decane; Aceto HMT; Aminoform; Aminoformaldehyde; Ammoform; Ammonioformaldehyde; Antihydral; Cystamin; Cystogen; Duirexol; Ekagom H; Esametilentetramina [Italian]; Formamine; Formin; Formin (heterocycle); HMT; Herax UTS; Heterin; Hexa (vulcanization accelerator); Hexa-Flo-Pulver; Hexaform; Hexaloids; Hexamethylenamine; Hexamethyleneamine; Hexamethylenetetraamine; Hexamethylenetetramine; Hexamethylenetetraminum; Hexamethylentetramin [German]; Hexamethylentetramine; Hexamethylentetraminum; Hexamine; Hexamine (heterocycle); Hexaminum; Hexasan; Hexasan (VAN); Hexilmethylenamine; Metenamina [INN-Spanish]; Methenamin; Methenamine; Methenaminum [INN-Latin]; Metramine; Nocceler H; Preparation AF; Resotropin; S 4 (heterocycle); Sanceler H; Uramin; Uratrine; Uritone; Urodeine; Urotropin; Urotropine; Vulkacit H 30; Xametrin; [ChemIDplus] UN1328

Category

Amines, Aliphatic

Description

White, crystalline powder or colorless, lustrous crystals; [HSDB]

Sources/Uses

Used in adhesives, coatings, sealants, and leather preservatives; also used as an anticorrosion agent, antibiotic, dye fixative, chemical stabilizer, and curing agent for formaldehyde resins and rubber; [HSDB] Used as a drug (methenamine) taken by mouth to prevent recurrent urinary tract infections; [Medscape DrugInfo] Used as a hardener for epoxy resins of the bisphenol A type; Used in the tire, rubber, foundry, and phenol-formaldehyde resin industries; Sometimes used in topical drugs and cosmetics; [Kanerva, p. 1811] Used as a formaldehyde releaser for photographic film development. [Kanerva, p. 1054-5]

Comments

A skin and eye irritant; A skin sensitizer; May cause asthma; [ICSC] Danger of skin sensitization; [MAK] TLV Basis is dermal sensitization. No evidence of increased risk of occupational asthma at concentrations of 0.2-2.6 mg/m3.

Biomedical References

1 mg/m3, inhalable fraction and vapor

0.004 mm Hg

Explanatory Notes

Flash point = 482 deg F; VP from ACGIH;

Reference Link #2

Yes

Not Classifiable

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Leather Tanning and Processing
• Molding and Core Making
• Painting (Pigments, Binders, and Biocides)
• Photographic Processing
• Plastic Composites Manufacturing
• Working with Glues and Adhesives