Chloral hydrate
Agent Name
Chloral hydrate
CAS Number
302-17-0
Formula
C2-H3-Cl3-O2
Major Category
Other Classes
Synonyms
1,1,1-Trichloro-2,2-dihydroxyethane; 1,1,1-Trichloro-2,2-ethanediol; 2,2,2-Trichloro-1,1-ethanediol; Aquachloral; Bi 3411; Chloradorm; Chloral monohydrate; Chloraldural [Swiss]; Chloraldurat [German]; Chloralex; Chlorali Hydras; Chloralvan; Cohidrate; Dormal; Escre; Felsules; Hydrate de chloral; Hynos; Kessodrate; Kloralhydrat; Knockout drops; Lorinal; Noctec; Novochlorhydrate; Nycoton; Nycton; Oradrate; Phaldrone; Rectules; SK-Chloral Hydrate; Somni SED; Somnos; Sontec; Tosyl; Trawotox; Trichloracetaldehyd-hydrat [German]; Trichloroacetaldehyde hydrate; Trichloroacetaldehyde monohydrate; Trichloroacetaldehyde, hydrated; [ChemIDplus]
Category
Halogenated Alcohols
Description
Colorless transparent solid with a penetrating, slightly acrid odor; [Hawley] Colorless or white solid; Colorless liquid; [HSDB] Crystalline solid; [MSDSonline]
Sources/Uses
Used as a drug (sedative and hypnotic), a rubefacient and liniment, a glue peptizing agent, and a chemical intermediate; [HSDB] Formed as by-product of drinking water chlorination; [IPCS]
Comments
A skin, eye, and respiratory tract irritant; A CNS depressant; [ICSC] A skin and mucous membrane irritant; May cause eye injury; [HSDB] A skin and eye irritant; [eChemPortal: ERMA; ESIS] An irritant; [MSDSonline] Liver injury reported after lethal doses, but not after therapeutic doses; [INCHEM: CICADS]
Biomedical References
Exposure Assessment
Vapor Pressure
15 mm Hg
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Probable (2a)
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: