Sodium omadine
Agent Name
Sodium omadine
CAS Number
15922-78-8; 3811-73-2
Formula
C5-H5-N-O-S.Na
Major Category
Other Uses
Synonyms
15922-78-8: Pyrithione sodium; 1-Hydroxy-2(1H)-pyridinethionato sodium; 1-Hydroxy-2(1H)-pyridinethione, sodium salt; AL02725; Omacide 24; Omadine-sodium; SQ 3277; Sel de sodium de 1-hydroxy-2 (1H)-pyridinethione [French]; Sodium 1-hydroxypyridine-2-thione; Sodium 2-pyridinethiol-1-oxide; Sodium Omadine; Sodium pyrithione; 2(1H)-Pyridinethione, 1-hydroxy-, sodium; [ChemIDplus]
3811-73-2: 2-Pyridinethiol, 1-oxide, sodium salt; Sodium (2-pyridylthio)-N-oxide; Sodium pyrithione; (1-Hydroxy-2-pyridinethione), sodium salt; (1-Hydroxy-2-pyridinethione), sodium salt, tech.; 1-Oxo-2-pyridinethiol sodium salt; 2-Mercaptopyridine 1-oxide sodium salt; 2-Mercaptopyridine oxide sodium salt; 2-Mercaptopyridine-N-oxide sodium salt; 2-Pyridinethiol N-oxide sodium salt; 2-Pyridinethiol-1-oxide sodium salt; Omadine sodium; Sodium (2-pyridylthio)-N-oxide; Sodium 2-mercaptopyridine 1-oxide; Sodium 2-pyridinethiol 1-oxide; Sodium 2-pyridinethiol N-oxide; Sodium 2-pyridinethiolate 1-oxide; Sodium omadine (VAN); Sodium, (2-pyridinylthio)-, N-oxide; Thione (reagent); [ChemIDplus]
Category
Biocides/Disinfectants
Description
Technical product is off-white solid; Formulated as liquid soluble concentrates; [Reference #1] 3811-73-2: Hygroscopic crystalline powder with a stench; [Alfa Aesar MSDS]
Sources/Uses
Used as biocide (controls slime forming bacteria and fungi) in aqueous functional fluids (metalworking, cutting, cooling, and lubricating), latex emulsions (adhesives, caulks, patching compounds, sealants, pastes, and grouts), aqueous fiber lubricants and inks, jet-printer inks, laundry rinse additives and detergents, carpet cleaners, analytical and diagnostic reagents; Also used as in-can preservative for water based mixtures used in making concrete (not covered in this RED); [Reference #1]
Comments
A mixture of two tautomers: 1-hydroxy-2(1H)-pyridinethione, sodium salt (15922-78-8) and 2-pyridinethio-1-oxide, sodium salt (3811-73-2); Not a skin sensitizer in guinea pig or human studies; Minimum to marked hind-limb atrophy observed in 13-week gavage study of rats at highest tested dose of 8 mg/kg/day (LOEL of 2 mg/kg/day based on evidence of neurotoxicity); [Reference #1] 3811-73-2: A skin and strong eye irritant; Harmful by ingestion; [Alfa Aesar MSDS]
Reference Link #1
Biomedical References
Exposure Assessment
MAK
0.2 mg/m3, inhalable fraction
Vapor Pressure
7E-08 mm Hg
Lethal Concentration
LC50 (rat) = 1,080 mg/m3/4hr
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: